Anomers vs. Epimers: Key Differences in Carbohydrate Stereochemistry
Anomers are cyclic carbohydrate epimers differing only at the anomeric carbon (C-1 or C-2 in ketoses), labeled α or β based on the new –OH orientation. Epimers are any stereoisomers that differ at exactly one chiral center other than the anomeric carbon. Students often lump them together because both describe single-center carbohydrate tweaks. Picture tasting…