Desmosomes vs Hemidesmosomes: Key Structural & Functional Differences Explained
Desmosomes are rivet-like junctions between two adjacent cells, locking them together so tissues resist shear. Hemidesmosomes look similar but anchor a single epithelial cell to the basement membrane beneath it, not to another cell. Medical students stare at EM slides where both appear as dark “spots” on membranes, so they mix them up. Clinicians see…